Delayed Diagnosis of Hepatitis C Infection: Results of a Nationwide US Study.

ABSTRACT:

Introduction

Universal screening of hepatitis C virus (HCV) was encouraged for individuals born 1945-65 in the USA in 2012. In 2014, efficacious treatments, namely, direct-acting antivirals (DAAs), were introduced. To examine their impact on the HCV care cascade, the proportion of and factors associated with delayed HCV diagnosis in the USA were examined in a national real-world cohort.

Methods

We retrospectively analyzed 69,989 adults with an HCV-related liver complication using the Merative™ Marketscan® Medicare Database (1/2007-12/2021). We defined delayed HCV diagnosis as a HCV diagnosis 2 years prior to or any time after the development of a liver complication, including cirrhosis, liver transplant, or hepatocellular carcinoma.

Results

The cohort mean age was 55.

SUBMITTER: Levesley CR 

PROVIDER: S-EPMC12646488 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature