Global Burden of Depressive Disorders, 1990-2021, During the COVID-19 Pandemic and Projections to 2050: A Global Burden of Disease Study 2021.

ABSTRACT:

Objective

Despite an increase in the depressive disorders burden during the coronavirus disease-2019 (COVID-19) pandemic, research remains insufficient. This study aims to advance the understanding of the global depressive disorders burden, focusing on the COVID-19 pandemic.

Methods

Global and regional estimates of incidence, prevalence, and disability-adjusted life years (DALYs) for depressive disorders from 1990 to 2021 were analyzed using the Global Burden of Disease Study 2021. Depressive disorders were defined as the aggregate of major depressive disorder and dysthymia. Estimates were stratified by age, sex, Socio-demographic Index (SDI), and region, and trends were assessed by annual percent change. Attributable risk factors and projections to 2050 were assessed by mod

SUBMITTER: Lee E 

PROVIDER: S-EPMC12646708 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature