A Randomized Controlled Trial of Group-Based Acceptance and Commitment Therapy for Major Depressive Disorder.

ABSTRACT:

Objective

Major depressive disorder (MDD) is a prevalent and debilitating psychiatric condition. This study developed a group-based acceptance and commitment therapy (GACT) program for MDD and conducted a randomized controlled trial to evaluate its effectiveness. The study aims to assess the effects of GACT and identify factors influencing depression recovery in patients with MDD in Korea.

Methods

Individuals diagnosed with MDD, aged 18-40 years, were recruited. Fifty-nine participants were randomly assigned to either the GACT or waitlist control (WLC) group, with 50 participants (27 in GACT and 23 in WLC) successfully completing the program.

Results

The GACT group demonstrated significant improvements in depression symptoms (Center for Epidemiological Studies-Depress

SUBMITTER: Lee SW 

PROVIDER: S-EPMC12646709 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature