Distribution and Clinical Profile of Human Parainfluenza Viruses in Hospitalized Patients With Acute Febrile Illness.

ABSTRACT:

Introduction

Human parainfluenza viruses (HPIVs) are significant causes of respiratory infections, particularly in children, yet their epidemiology remains poorly understood in low- and middle-income countries. HPIVs contribute to 20%-40% of pediatric lower respiratory tract infections (LRTIs) and are a leading cause of croup and hospitalizations. This study was aimed at determining the incidence, distribution, and clinical and laboratory characteristics of HPIV in hospitalized acute febrile illness (AFI) patients.

Methods

A total of 12,409 AFI cases from 2016 to 2018 were tested for HPIVs via molecular methods. RNA was extracted from throat swab samples and tested via multiplex real-time RT-PCR for HPIV Serotypes 1-4. The demographic, clinical, and laboratory data of HPIV-p

SUBMITTER: Devadiga S 

PROVIDER: S-EPMC12646732 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature