Diagnostic Efficacy and Correlation of Intravoxel Incoherent Motion (IVIM) and Contrast-Enhanced (CE) MRI Perfusion Parameters in Oncology Imaging: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

Intravoxel incoherent motion (IVIM) magnetic resonance imaging (MRI) is a noncontrast technique estimating diffusion and perfusion parameters via multiple b-values, essential for oncology imaging. However, there is limited collective evidence regarding the efficacy of IVIM in oncology imaging compared to contrast-enhanced (CE) MRI perfusion techniques. This systematic review and meta-analysis compared IVIM's diagnostic accuracy and correlation with CE MRI perfusion techniques.

Methods

Following PRISMA guidelines (PROSPERO-registered), a literature search across five databases (PubMed, Scopus, Embase, Web of Science, and Cochrane Library) was conducted. Diagnostic metrics, including AUC, sensitivity, specificity, and correlation coefficients, were analyzed u

SUBMITTER: S A 

PROVIDER: S-EPMC12646736 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature