Assessment of High-Volume Antibiotic and Opioid Prescribing by Medicare Part D Prescribers-United States, 2021.

ABSTRACT: Characterizing high-volume co-prescribing of antibiotics and opioids can inform interventions that improve prescribing practices. Using 2021 Medicare Part D data, we conducted a cross-sectional analysis to assess concordance between high-volume prescribing of antibiotics and opioids and characterize associations between prescriber-level factors and high-volume co-prescribing of antibiotics and opioids. High-volume antibiotic prescribers accounted for 12.5 million (36.0%) antibiotic prescriptions, and high-volume opioid prescribers accounted for 22.3 million (51.9%) opioid prescriptions. We found fair concordance between being a high-volume prescriber of antibiotics and a high-volume prescriber of opioids (κ = 0.30). Prescribers in the South (adjusted odds ratio [AOR] = 3.67; 95% CI, 3.46-3

SUBMITTER: Vazquez Deida AA 

PROVIDER: S-EPMC12646945 | biostudies-literature | 2026 Mar-Apr

REPOSITORIES: biostudies-literature