Prevalence, Age of Onset, Age at Diagnosis, and Family History of Hidradenitis Suppurativa in Pediatric Populations: A Systematic Review and Meta-Analysis.

ABSTRACT:

Introduction

Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition characterized by recurrent nodules and abscesses in intertriginous areas, ultimately resulting in scarring and formation of sinus tracts. HS significantly impacts quality of life and can also affect pediatric populations. We aimed to determine the prevalence, family history, age of onset, and age at diagnosis of HS in pediatric populations.

Methods

A random-effects meta-analysis of observational studies was conducted following MOOSE guidelines. Five databases were searched through May 2024.

Results

Thirty seven observational studies were included, representing 6941 patients from 13 countries. The weighted mean age was 14.7 years (range: 4-18). Ethnoracial distribution included White (3

SUBMITTER: Xiong G 

PROVIDER: S-EPMC12646978 | biostudies-literature | 2025 Nov-Dec

REPOSITORIES: biostudies-literature