Global, regional, and national burden of pediatric nasopharyngeal carcinoma (1990-2021) and projections of future disease burden trends.

ABSTRACT:

Objective

Pediatric nasopharyngeal carcinoma (NPC) is an exceedingly rare and often overlooked disease. However, early detection of this condition is a decisive factor in its prognosis. This study aims to quantify the disease burden and epidemiological trends of pediatric nasopharyngeal carcinoma over a 30-year period (1991-2021) and provide projections for future disease burden.

Methods

Comprehensive data on pediatric NPC from 1990 to 2021 were obtained from the Global Burden of Disease study. This dataset includes information on the incidence of pediatric NPC, disaggregated by gender. The Joinpoint regression model was used to identify turning points in epidemiological trends, while decomposition analysis helped identify the factors driving these trends. To forecast future

SUBMITTER: Xu Y 

PROVIDER: S-EPMC12647026 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature