Delayed orthostatic hypotension in Parkinson's disease and in the general ageing population.

ABSTRACT:

Objective

Delayed orthostatic hypotension (dOH) is defined by a sustained blood pressure (BP) fall ≥20/10 mmHg occurring beyond 3 minutes in the upright position, whose clinical relevance is yet undetermined. We investigated frequency, associated features and treatment strategies of dOH in Parkinson's Disease (PD) and ageing individuals with history of syncope or orthostatic intolerance.

Methods

We retrospectively studied 213 individuals with PD and 213 age-matched individuals without parkinsonism referred for tilt-table testing to the Innsbruck and Florence Dysautonomia centres. In both cohorts, we reviewed the medical records of the 6 months before testing for history of syncope and falls, and of the 6 months afterwards for the recommended dOH treatment and clinical outcom

SUBMITTER: Calio B 

PROVIDER: S-EPMC12647057 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature