Global, regional, and national burden of ischemic heart disease in young and middle-aged population from 1990 to 2021.

ABSTRACT: Early-onset ischemic heart disease (IHD) is an emerging global health concern. Quantifying its burden and key risk factors is essential for effective prevention and control. This study utilizes the data from Global Burden of Disease Study 2021 to analyze the burden of IHD in young and middle-aged population (15-49 years old), including prevalence, incidence, deaths and disability-adjusted life years (DALYs) from 1990 to 2021. Attributable risk factors were assessed across different sex and region, and trends were analyzed using age-standardized rate (ASR) and average annual percentage change (AAPC). In 2021, the ASR of prevalence and incidence showed an increasing trend, with AAPCs of 0.26% (95% confidence interval [CI], 0.24% to 0.29%) and 0.23% (95%CI, 0.09% to 0.38%), respectively; the

SUBMITTER: Song J 

PROVIDER: S-EPMC12647134 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature