The Impact of Intravesical Instillations on Quality of Life in Patients with Non-Muscle-Invasive Bladder Cancer: A Systematic Review.

ABSTRACT:

Background

Non-muscle invasive bladder cancer (NMIBC) is commonly treated with transurethral resection of bladder tumor (TURBT) followed by intravesical chemotherapy and/or Bacillus Calmette-Guérin (BCG) instillations. While these treatments aim to prevent recurrence and progression, the frequency of their administration and associated side effects can substantially impact patients' quality of life (QoL).

Objectives

We aimed to systematically review the impact of intravesical BCG and chemotherapy instillations on QoL in patients with NMIBC, with a specific focus on how instillation frequency influences treatment adherence and withdrawal rates.

Methods

A systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-ana

SUBMITTER: Griebsch I 

PROVIDER: S-EPMC12647504 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature