High Prevalence and Genomic Characterization of Extended-Spectrum <b>β</b>-Lactamase-Producing <i>Escherichia coli</i> in the Yellow River and Source Water from A One Health Perspective - Henan Province, China, 2023-2024.

ABSTRACT:

What is already known about this topic?

The Yellow River serves as a significant conduit for antibiotic resistance transmission from environmental reservoirs to human populations. However, the occurrence and transmission pathways of the clinically relevant extended-spectrum β-lactamase (ESBL) gene bla _CTX-M-G9 and ESBL-producing Escherichia coli (E. coli) within the Yellow River remain poorly characterized.

What is added by this report?

This study reveals the widespread prevalence of bla _CTX-M-G9 throughout the Yellow River and its associated water sources in Henan Province, and demonstrates the environmental dissemination and probable animal origin of the dominant E. coli sequence type (ST) 6802 harboring the bla</

SUBMITTER: Tian T 

PROVIDER: S-EPMC12647939 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature