Spatially Resolved Ion Sensing by Voltammetric Ion Transfer Microscopy.

ABSTRACT: The visualization and mapping of ionic species in solution and near surfaces are important to understand chemical gradients and spatially resolved dynamic processes in various fields. Available label-free approaches are either slow or restricted to a few parameters, such as pH. We introduce here a novel chemical mapping principle for the spatially resolved sensing of optically silent ionic species at high frequency, acquiring a concentration map of millions of pixels in seconds using a conventional fluorescence microscope. The principle relies on ion transfer from a thin polymeric film into a solution phase, electrochemically coupled to electron transfer at the back side of the film. Different solution concentrations change the potential at which ion transfer is observed, which is visualiz

SUBMITTER: Mattos GJ 

PROVIDER: S-EPMC12648306 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature