Early Life Exposure to the Great Chinese Famine and Cardiometabolic Outcomes.

ABSTRACT:

Importance

Epidemiologic studies suggest that people who were exposed to famine during early life but now live in nutrient-abundant environments have an elevated risk of type 2 diabetes (T2D) and other cardiometabolic conditions. Although many individuals who were exposed to famine in early life have now immigrated to high-income countries, the association between early life famine exposure and cardiometabolic outcomes among immigrants is unknown.

Objective

To investigate the associations of early life exposure to the Great Chinese Famine with the incidence of T2D, hypertension, and cardiovascular hospitalization among immigrants.

Design, setting, and participants

This population-based cohort study in Ontario, Canada, used 3 cohorts (1 for each coprimary outcome of T2

SUBMITTER: Cao A 

PROVIDER: S-EPMC12648349 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature