Venous thromboembolism in obese hormonal contraceptive users: a large national database study.

ABSTRACT:

Objectives

This study aimed to assess the risk of venous thromboembolism (VTE) among obese and nonobese females aged 10 to 44 years prescribed hormonal therapy (HT) and compare VTE rates between different HT types in a large national database.

Methods

A retrospective cohort study was conducted using TriNETX data, which includes electronic health records and pharmaceutical claims from 81 million patients across 56 US tertiary care hospitals. Females prescribed HT between 2000 and 2022 were stratified by body mass index. VTE incidence was identified using International Classification of Diseases, Ninth/Tenth Revision, codes and anticoagulant prescriptions. Propensity score matching controlled for confounders.

Results

Of 4,020,467 females, 34% (1,370,481) were obese. VTE

SUBMITTER: Citla-Sridhar D 

PROVIDER: S-EPMC12648605 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature