Evaluation of microbiological efficacy of 2% chlorhexidine gluconate cloths versus 4% chlorhexidine gluconate soap for preoperative preparation/shower in total joint arthroplasty: a single-centre randomised controlled trial.

ABSTRACT:

Background

Preventing surgical site infections (SSI) is crucial and, among preventive measures, preoperative shower is recommended to decrease skin bacterial colonisation. However, there is no recommendation on the use of Chlorhexidine gluconate (CHG) impregnated cloths in this indication. The objective was to assess the microbiological efficacy of 2% CHG cloths for preoperative preparation/shower.

Methods

In this single-centre parallel group trial, patients were randomised (1:1) to receive either 2% CHG cloths (intervention) or 4% CHG soap (standard-of-care) the night before and the morning of the surgery. Samples were taken to assess skin bacterial colonisation in colony forming units (CFU)/cm² at the surgical site: before (T1) and after (T2) the first preparation/shower,

SUBMITTER: Gallouche M 

PROVIDER: S-EPMC12648918 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature