Fine-scale assessment of ROH patterns and genomic inbreeding in diverse horse breeds using two SNP array densities.

ABSTRACT:

Background

Inbreeding is caused by mating between related individuals and is associated with reduced fitness and performance. Generally, in the horse population, inbreeding is caused by geographically restricted areas and intensive natural or artificial selection. For this reason, assessing accurate inbreeding is essential for developing and implementing effective breeding strategies aimed at preserving genetic diversity and reducing the harmful consequences of inbreeding. One of the most accurate approaches for assessing genomic inbreeding and autozygosity is through the analysis of runs of homozygosity (ROH), which are long stretches of homozygous genotypes inherited from common ancestors and provide valuable insights into population diversity, demographic history, and selection.

SUBMITTER: Moghbeli Damane M 

PROVIDER: S-EPMC12648929 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature