Associations of single and multiple vitamin levels with pediatric oral mucosal diseases: a cross-sectional study with multi-model analysis.

ABSTRACT:

Background

Vitamins play a crucial role in children's oral health, yet the associations between multiple vitamins and pediatric oral mucosal diseases (OMDs) remain unclear. Existing studies often focus on single vitamin, leaving gaps in understanding the complex interactions of vitamin mixtures on OMDs and age-specific effects.

Methods

This cross-sectional study included 1,287 children from the Children's Hospital Affiliated to Zhengzhou University (January 2022 to April 2025), comprising 167 OMDs patients and 1,120 healthy controls. Participants were stratified into early childhood (0-6 years; n = 665) and school-age (6-12 years; n = 622) groups. Serum levels of vitamins A, D, E, C, B6, and B9 were measured. Individual and mixture effects on OMDs were assessed

SUBMITTER: Fang P 

PROVIDER: S-EPMC12648972 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature