Global, regional, national burden, trends and health inequality of neglected tropical diseases and malaria from 1990 to 2021.

ABSTRACT:

Background

Neglected tropical diseases and malaria (NTDM) remain persistent public health challenges, disproportionately affecting populations in low- and middle-income countries. This study aims to systematically evaluate the burden, trends, and health inequities of NTDM from 1990 to 2021, and to project trends through 2050.

Methods

This secondary analysis of the Global Burden of Disease (GBD) 2021 database assessed NTDM burden by age, sex, region, and Socio-Demographic Index (SDI). Temporal trends were assessed using joinpoint regression, health inequality was gauged with Concentration Index (CI) and Slope Index of Inequality (SII). Decomposition analysis quantified contributions of population growth, aging, and epidemiological shifts to NTDM burden changes. Bayesian age-p

SUBMITTER: Feng L 

PROVIDER: S-EPMC12649024 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature