Capturing Compensatory Reserve in Sarcopenia: A Bioengineering Framework for Multidimensional Temporal Analysis of Center-of-Pressure Signals.

ABSTRACT: Conventional balance assessments often miss subtle deficits in sarcopenia patients due to compensatory strategies. This study develops a computational framework using multidimensional temporal analysis of center-of-pressure (COP) signals to quantify variations in compensatory reserve-the capacity to mask balance impairments-within these patients. COP data were collected from 82 older adults (sarcopenia vs. controls) during static standing on a standard clinical force platform (routine for geriatric balance testing). The framework integrates Dynamic Time Warping distances from a healthy template, fixed-weight LSTM embeddings, and statistical metrics, with feature selection and 5-fold cross-validation (SMOTE) to mitigate overfitting. Semi-tandem stance was most discriminative, achieving 0.84

SUBMITTER: Zhao Q 

PROVIDER: S-EPMC12649375 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature