Widespread Distribution of Carbapenem-Resistant <i>Klebsiella</i> spp. in Clinical and Environmental Settings.

ABSTRACT: Background/Objectives:Klebsiella spp., particularly K. pneumoniae, are major opportunistic pathogens in healthcare settings driven by carbapenemase- and ESBL-producing strains. We assessed antimicrobial resistance and biofilm formation abilities in Klebsiella spp. from a Brazilian tertiary hospital and related environments and characterized capsular types. Methods: Over six months (July-December 2023), 303 carbapenem-resistant Klebsiella spp. were collected from clinical specimens (n = 198), ICU/non-ICU surfaces (n = 79), hospital sewage (n = 22), and stream water (n = 4). Species were identified by MALDI-TOF. Susceptibility testing covered eight antibiotic classes, focusing on carbapenems and polymyxin B. Biofilm

SUBMITTER: Maldonado KVM 

PROVIDER: S-EPMC12649591 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature