The German LAKE-score reliably predicts urinary and dietary potential renal acid load: a three-armed translational study.

ABSTRACT:

Background

Evidence supports kidney injury from a high potential renal acid load (PRAL). Existing predictive equations to estimate the PRAL have important limitations and require either a 24-h urine collection or the estimation of an individual's nutrient intake. The LAKE (load of acid to kidney evaluation) score offers a more pragmatic solution; however, the score has never been translated into the German language.

Materials and methods

We translated the LAKE score into German, and validated it in a three-armed study in a healthy population comprised of omnivores, lacto-ovo-vegetarians and vegans. Using weighed food diaries, we estimated the participants' dietary PRAL (PRAL_R). The urinary PRAL (_UPRAL) was calculated based on 24-h urine collection-deriv

SUBMITTER: Storz MA 

PROVIDER: S-EPMC12649776 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature