Vitamin D, C-Reactive Protein, and Cardiometabolic Risk Clustering in Middle-Aged Adults: Results from the 2023 Korea National Health and Nutrition Examination Survey (KNHANES).

ABSTRACT: Background/Objectives: Cardiometabolic risk clustering (CMRC), the coexistence of multiple risk factors, markedly increases the risk of cardiovascular disease and diabetes. While obesity is central, the independent roles of vitamin D status and systemic inflammation remain unclear. This study examined determinants of CMRC in middle-aged Korean adults, focusing on vitamin D and C-reactive protein (CRP). Methods: Cross-sectional data were analyzed from 2062 adults aged 40-64 years in the 2023 Korea National Health and Nutrition Examination Survey. CMRC was defined as ≥3 of abdominal obesity, hypertension, diabetes, hypertriglyceridemia, and low high-density lipoprotein cholesterol. Serum 25-hydroxyvitamin D [25(OH)D], CRP, lifestyle behaviors, and covariates were assessed. Comp

SUBMITTER: Lee C 

PROVIDER: S-EPMC12650019 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature