The Heterogeneity of Reading and Spelling Deficits in Posterior Cortical Atrophy.

ABSTRACT:

Background

Posterior Cortical Atrophy (PCA) is a clinical syndrome marked by progressive visuospatial impairment, usually due to underlying Alzheimer's disease. While reading and spelling deficits are recognized clinical features of this syndrome, the contributions of visuoperceptual versus linguistic deficits to these impairments are still unclear.

Methods

To that end, we examined reading and spelling performance in 23 individuals from the Massachusetts General Hospital PCA cohort. Participants completed tests of reading from the Western Aphasia Battery and spelling to dictation from the Boston Diagnostic Aphasia Examination. A mixed-methods analysis included quantitative scoring and qualitative observations of visual behaviors, error patterns, and compensatory strategies.<

SUBMITTER: Watson N 

PROVIDER: S-EPMC12650043 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature