Ecological History Shapes Transcriptome Variation in Quiescent <i>Saccharomyces cerevisiae</i>.

ABSTRACT: Quiescence is a pivotal state for all living organisms and cells. However, recent research indicates a lack of uniformity among quiescent cells. That is, even if the primary feature of quiescence-the ability to restart divisions-is maintained, quiescent cells within populations exhibit variation in their cellular architecture and characteristics. While it is known that the process of entry into quiescence is influenced by a combination of nutrient starvation and temporal factors, the underlying mechanisms remain to be fully elucidated. In this study, we compare the transcriptomes of known homogenous fractions of dense quiescent yeast isolated from populations of different ecological histories. These populations have undergone experimental enrichment of certain types of quiescent cells duri

SUBMITTER: Marek A 

PROVIDER: S-EPMC12650442 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature