Patterns of Management of Positive Sentinel Lymph Nodes in Breast Cancer Patients After the American College of Surgeons Oncology Group Z0011 Trial: A Retrospective Study.

ABSTRACT:

Background

Breast cancer is the most prevalent malignancy among women and the leading cause of cancer-related mortality. Sentinel lymph node biopsy (SLNB) has emerged as an alternative to axillary lymph node dissection (ALND), with the ACOSOG Z0011 trial demonstrating that SLNB alone yields equivalent oncologic outcomes to ALND for patients with 1-2 positive sentinel lymph nodes (SLNs).

Objective

This study evaluates the adoption of Z0011 recommendations at the American University of Beirut Medical Center (AUBMC) and their impact on oncologic outcomes.

Methods

This retrospective cohort study includes female patients with early-stage breast cancer (T1-T2, N0, M0) who underwent breast-conserving surgery with SLNB at AUBMC, between January 2011 and December 2016. Data we

SUBMITTER: El Charif MH 

PROVIDER: S-EPMC12650466 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature