Targeting Executive Function and Language Impairments with tACS Combined with Behavioral Intervention in Primary Progressive Aphasia: A Case-Series, Pilot Investigation.

ABSTRACT: Background/Objectives: Executive function (EF) impairments are found in a variety of neurodegenerative disorders, including in Primary Progressive Aphasia (PPA), which is primarily characterized by language impairments. The goal of this preliminary investigation was to evaluate the hypothesis that, by targeting domain-general EFs, domain-specific functions-specifically, language processing-might also be improved in this population. Methods: This case series included four Greek-speaking individuals with PPA who underwent behavioral and neurostimulation treatment daily for 15 consecutive sessions. Behavioral treatment was performed through Computerized Cognitive Training (CCT) that targeted various EF functions. Neurostimulation treatment included alpha-rhythm transcranial alte

SUBMITTER: Neophytou K 

PROVIDER: S-EPMC12650604 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature