Effect of Different Prebiotic Saccharides on <i>Listeria monocytogenes</i> Adherence to Human Adenocarcinoma Caco-2 Cell Line.

ABSTRACT: Listeria monocytogenes (LM) is one of the most emerging pathogens responsible for the serious foodborne disease listeriosis. The risk of disease outbreaks can be reduced by suppressing the adherence of LM to the intestinal epithelial cells. This effect can be achieved by prebiotic supplementation. The aim of this work was to determine the effect of prebiotics beta-(1,3)-D-glucan, inulin, fructooligosaccharides, galactooligosaccharides, lactulose, raffinose, stachyose, human milk oligosaccharides (HMOs), and 2'-fucosyllactose on the ability of LM to adhere to the human adenocarcinoma Caco-2 cell line. Despite strain-specific variability, a statistically significant reduction in LM adhesion to intestinal epithelial cells was observed in the presence of beta-(1,3)-D-glucan (~60% reduct

SUBMITTER: Kodesova T 

PROVIDER: S-EPMC12650974 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature