Fear of disease progression and relapse in multiple sclerosis: a systematic scoping review.

ABSTRACT:

Background

Multiple sclerosis (MS) is a chronic disease of the central nervous system, most commonly affecting individuals in early adulthood. Uncertainty about future relapses and accumulating disability may lead to significant psychological distress, contributing to reduced quality of life.

Objective

This systematic scoping review aimed to synthesize current evidence on the prevalence, determinants, and consequences of fear of relapse and disease progression in people living with MS.

Method

The current systematic scoping review followed PRISMA-ScR guidelines. PubMed, Scopus, and Web of Science were searched from inception until October 6^th. Original, English-language studies investigating fear of disease progression or relapse among people with multiple s

SUBMITTER: Mallahzadeh A 

PROVIDER: S-EPMC12651443 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature