Age-Related Associations of Blood Pressure and Arterial Stiffness with Retinal Arterial Structure.

ABSTRACT:

Objective

To investigate the associations of systolic blood pressure (SBP) and arterial stiffness, measured via the cardio-ankle vascular index (CAVI), with retinal arterial structure assessed by OCT, and examine age-related differences.

Design

A cross-sectional analysis of a community-based Japanese cohort.

Participants

A total of 6969 adults (mean age, 57.6 years; 69.6% women) who underwent OCT imaging between 2012 and 2016.

Methods

Peripapillary circular OCT B-scans were used to assess the 4 largest retinal arteries. OCT-derived parameters included outer diameter (OD), inner diameter (ID), wall thickness, and wall reflectivity. Multivariable linear regression adjusted for demographic, ocular, and systemic covariates. Interaction analyses evaluated age modifi

SUBMITTER: Xiang R 

PROVIDER: S-EPMC12651487 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature