Integrated Transcriptomic and Metabolomic Analysis Reveals <i>VASH1</i> Influences Pork Quality by Regulating Skeletal Muscle Glycolysis.

ABSTRACT: Glycolytic potential (GP) is an important index for evaluating meat quality in the pig industry, since high muscle glycogen content generally leads to rapid postmortem glycolysis, which contributes to low meat quality. The natural differences in meat quality between Chinese local pigs (good meat quality) and Western pigs (standard meat quality) make them the ideal models for glycolysis research. Here, we investigated the mechanisms of glycolysis through comparing transcriptome and metabolome data of biceps femoris (BF) muscle between Jinhua (JH) and Landrace × Yorkshire (LY) pigs at different ages. In this research, JH pigs exhibited lower intramuscular glycogen content than LY pigs throughout the growth period (p < 0.05). Increased phosphorylated glycogen synthase (p-GS) exp

SUBMITTER: Wu F 

PROVIDER: S-EPMC12651661 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature