Catecholaminergic Adaptation to Extreme Military Stress: Norepinephrine and Dopamine Responses During and After SERE Training.

ABSTRACT: Catecholamines are fundamental mediators of the stress response, regulating arousal, vigilance, and adaptive behavior. However, their dynamics under extreme real-life conditions remain insufficiently explored. Survival, Evasion, Resistance, and Escape (SERE) training provides a unique model for examining neuroendocrine mechanisms of adaptation during both the acute phase and the recovery period following intense psychological and physical stress. Serum norepinephrine (NE) and dopamine (DA) were measured in 47 special forces soldiers during peak stress in SERE and one month later, compared with 17 healthy controls. Samples were collected under standardized conditions and analyzed using validated ELISA kits. NE levels differed significantly among groups (p = 0.003), being higher durin

SUBMITTER: Grzesik-Pietrasiewicz M 

PROVIDER: S-EPMC12651961 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature