Integrated Transcriptomic and Metabolomic Analyses Reveal Key Genes Involved in Phenylpropanoid Metabolism in <i>Lonicera macranthoides</i> Flowers.

ABSTRACT:

Background

Lonicera macranthoides (L. macranthoides) is a traditional Chinese medicinal plant, the flower buds of which are rich in bioactive compounds, such as chlorogenic acids (CGAs) and flavonoids, and exhibit diverse pharmacological activities.

Methods

Integrated transcriptomic and metabolomic analyses were conducted across three floral developmental stages: flower bud (FB), white flower (WF), and golden flower (GF).

Results

Clustering analysis revealed distinct molecular profiles, with the WF and GF stages clustering together and clearly separating from the FB stage. The most significant metabolomic variation was observed between the GF and FB stages. KEGG enrichment analysis consistently highlighted the phenylpropanoid biosynthesis pathway as a ke

SUBMITTER: Li Z 

PROVIDER: S-EPMC12651994 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature