RNAi-Based Bioinsecticides for Controlling Vector-Borne Diseases.

ABSTRACT: Vector-borne diseases account for 17% of all infectious diseases. The most effective strategies for controlling these diseases have focused on decreasing the vector population, primarily through the use of insecticides. Many insecticides have no specific targets, harming pollinators and beneficial insects. Additionally, the vector populations are developing resistance, reducing the effectiveness of these strategies and increasing ecological damage. Double-strand RNA (dsRNA) is widely used in insects to study gene function by knocking down their expression. Recently, this technology has been applied to develop RNAi-based insecticides for controlling agricultural pests. These biopesticides demonstrate high specificity, as insects do not develop resistance to them, and they cause minimal ecol

SUBMITTER: Maya-Maldonado K 

PROVIDER: S-EPMC12652134 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature