Toxicological Effects of Titanium Dioxide Nanoparticles on Human Menstrual Blood Mesenchymal Stem Cells.

ABSTRACT: Human exposure to titanium dioxide nanoparticles (TiO₂ NPs) is common. These NPs are used in cosmetics, paint, food, and other products. Their nanometric size (<100 nm) allows entry into the bloodstream, from which they can reach organs and cells throughout the body. Although TiO₂ NPs have been reported to damage certain cell lines and organs and to alter cellular function, their impact on human menstrual blood mesenchymal stem cells (hMB-MSCs) is unknown. This study evaluated the effects of TiO₂ NPs on viability, proliferation, morphology, membrane-marker expression, and reactive oxygen species (ROS) production in primary cultures of hMB-MSCs derived from menstrual blood. Cells were exposed to different concentrations of TiO₂ NPs for 3, 7, and 1

SUBMITTER: Parra-Barrera A 

PROVIDER: S-EPMC12652598 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature