Force Reversal During Systolic-Diastolic Transition Provides Incremental Prognostic Value over LVEF for Heart Failure After STEMI.

ABSTRACT: Background: Left ventricular hemodynamic forces (LV HDFs) are altered in myocardial dysfunction. While infarct location and size influence post-ST-segment elevation myocardial infarction (STEMI) remodeling, their specific effects on HDFs remain unclear. This study investigated how infarct location and size impact left ventricular HDFs and assessed HDFs' prognostic value for predicting subsequent heart failure (HF) in STEMI patients. Methods: In this retrospective study, 275 STEMI patients underwent cardiac magnetic resonance (CMR) 3-7 days after primary percutaneous coronary intervention. HDFs were derived from routine CMR cine images. Patients were stratified by infarct location (anterior vs. non-anterior) and median infarct size (IS). Key parameters-apical-basal (A-B) and l

SUBMITTER: Sun Y 

PROVIDER: S-EPMC12653228 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature