Virulence Plasmid Modulates Glucose-Mediated Biofilm Regulation in <i>Yersinia enterocolitica</i>.

ABSTRACT: Yersinia enterocolitica is a foodborne pathogen capable of biofilm formation and virulence modulation in response to environmental signals. Among these, glucose-present at physiologically relevant concentrations in the human body-may serve as a regulatory cue affecting infection-associated pathways, including those governed by the pYV virulence plasmid. Although the role of glucose has been investigated under host-mimicking conditions, its impact in non-host environments remains poorly understood. This study was designed to evaluate the glucose-dependent physiological responses of two isogenic Y. enterocolitica strains, KT0001 (pYV-negative) and KT0003 (pYV-positive), under non-host conditions (26 °C). Both strains were cultured in TYE medium containing 0-3% glucose. Comparat

SUBMITTER: Oh Y 

PROVIDER: S-EPMC12653292 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature