Guiding Antibiotic Therapy with Machine Learning: Real-World Applications of a CDSS in Bacteremia Management.

ABSTRACT: Bacteremia is a life-threatening condition contributing significantly to sepsis-related mortality worldwide. With delayed appropriate antibiotic therapy, mortality increases by 20% regardless of antimicrobial resistance. This study evaluated the perceived clinical utility of Artificial Intelligence (AI)-powered Clinical Decision Support Systems (CDSSs) (OneChoice and OneChoice Fusion) among specialist physicians managing bacteremia cases. A cross-sectional survey was conducted with 65 unique specialist physicians from multiple medical specialties who were presented with clinical vignettes describing patients with bacteremia and 90 corresponding AI-CDSS recommendations. Participants assessed the perceived helpfulness of AI decision-making, the impact of AI recommendations on their own clini

SUBMITTER: Gomez de la Torre JC 

PROVIDER: S-EPMC12653489 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature