Genetic Association of Mood Swings with Lung Function and Respiratory Diseases.

ABSTRACT: Background: Observational studies have linked psychotic disorders to impaired lung function and respiratory diseases, but the potential association between mood swings-a potential predisposing factor for psychotic disorders-and lung health remains poorly understood. Methods: Using summary-level data from large-scale genome-wide association studies, we investigated the shared genetic basis and putative causal links between mood swings and lung function, asthma, and chronic obstructive pulmonary disease (COPD). Results: Evident genetic correlations in our study were observed between mood swings and FEV1 (r_g = -0.09), FVC (r_g = -0.09), PEF (r_g = -0.09), asthma (r_g = 0.33), and COPD (r_g</

SUBMITTER: Ku Y 

PROVIDER: S-EPMC12653518 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature