Pediatric Burns: Biological and Tissue Engineered Skin Substitutes-A Systematic Review.

ABSTRACT: Background/Objectives: Surgical debridement and early excision of burned areas followed by skin autograft is the gold standard of treatment for partial and full-thickness pediatric burns. However, skin autografting might be unfeasible or unlikely to succeed due limited availability of skin donor areas or inadequate conditions. In these circumstances, alternative treatment is required, and Skin Substitutes (SS) cold play a role. Recently, Biological Skin Substitutes (BSS) and Tissue Engineered Skin Substitutes (TESS) are emerging as alternative treatment options, but strong evidence is missing. This review investigates the current literature focusing on BSS and TESS, aiming to improve the medical and surgical management of pediatric patients. Methods: A systematic review was p

SUBMITTER: Susini P 

PROVIDER: S-EPMC12653667 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature