The Gene Ail for the Attachment-Invasion Locus Protein of <i>Yersinia enterocolitica</i> Biotype 1A Strains Is Located on the Genomes of Novel Prophages.

ABSTRACT: The attachment-invasion locus protein Ail of pathogenic Yersinia strains is an important virulence factor, both for invasion of eucaryotic cells and for serum resistance. In other Yersinia strains, e.g., those belonging to biotype (BT) 1A of Yersinia enterocolitica, ail has only occasionally been described. Sequence analysis of 370 BT 1A isolates in our laboratory revealed 41 (11.1%) which were ail-positive. Most of these isolates were recovered from minced meat and tonsils of wild boars, and belonged to 17 MLST allele profiles. A closer look at DNA sequences surrounding ail disclosed that the gene in most isolates is embedded in DNA regions encoding phage proteins. The genomes of four prophages belonging to four different phylogenetic clusters wer

SUBMITTER: Hammerl JA 

PROVIDER: S-EPMC12653942 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature