Waist Circumference as an Independent Marker of Insulin Resistance: Evidence from a Nationwide Korean Population Study.

ABSTRACT: Background: Waist circumference (WC) has become an essential diagnostic marker of metabolic syndrome; however, its accuracy in reflecting insulin resistance remains uncertain, particularly among Asian people who develop metabolic complications at lower levels of adiposity. Methods: We analyzed 20,202 adults (8886 men and 11,316 women) from the Korean National Health and Nutrition Examination Survey (KNHANES) 2015 and 2019-2021. All analyses accounted for the survey sampling weights and the complex survey design. WC, insulin resistance, and β-cell function were assessed using fasting insulin level, HOMA-IR, and HOMA-β. Associations between WC and insulin indices were evaluated using correlation analyses, stratification by WC deciles, and multivariable regression models adjuste

SUBMITTER: Lim SH 

PROVIDER: S-EPMC12653953 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature