The Gastric Microbiome Communities and Endoscopic Mucosal Morphologies Associated with Premalignant Conditions.

ABSTRACT: The risk of Helicobacter pylori (H. pylori)-related gastric tumorigenesis is closely associated with the degree of chronic gastritis, although other gastric mucosa microbes may be relevant in this process. The morphological identification of the gastric mucosa associated with the cancer-promoting microbiome may have important implications for gastric cancer prevention. This study characterized gastric mucosa microbiome communities in relation to their mucosal morphologies. A total of 94 biopsies from non-neoplastic gastric bodies underwent 16S rRNA sequencing. Microbiome structures were characterized in relation to their mucosal morphologies, which were obtained using narrow-band imaging with magnifying endoscopy. H. pylori infection- and inflammatory mucosa-associated

SUBMITTER: Shijimaya T 

PROVIDER: S-EPMC12654504 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature