Inactivation of Respiratory Syncytial Virus by Ozone Generated via Dielectric Barrier Discharge Technology with Decrease in Intact Viral Surface Protein.

ABSTRACT: Respiratory syncytial virus (RSV) is a major cause of severe respiratory infections, particularly in infants and young children. Although disinfection methods using alcohol and detergents are effective, their application in pediatric environments poses safety concerns. Ozone (O₃) has been employed for water treatment, food preservation, and air purification, but its efficacy against RSV has not been well studied. Here, we investigated the inactivation of RSV using a dielectric barrier discharge (DBD)-based ozone generator (SFG1210). The RSV A2 strain was spotted on glass coverslips and exposed to low-concentration ozone (0.5 ppm) for 1 h under controlled temperature (24.6~27.2 °C) and relative humidity (71.9~75.1%) conditions. Subsequent infectivity assays combined with immunoch

SUBMITTER: Sakudo A 

PROVIDER: S-EPMC12654626 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature