Genomic Drivers of Biofilm Formation in <i>Salmonella</i> Enteritidis and <i>S</i>. Kentucky from Poultry Production.

ABSTRACT: Salmonella Enteritidis (SE) remains a leading cause of human illness worldwide, and its persistence in poultry environments might be partially attributed to their ability to form biofilm. This study compared the biofilm capacity of 15 SE and 24 Salmonella Kentucky (SK) isolates from poultry products and processing facilities to uncover genetic factors driving biofilm heterogeneity. Biofilm formation and curli/cellulose production were evaluated at 20-22 °C. Genomic analyses included phylogenetic reconstruction, comparative system profiling, SNP variation, and BLASTp v2.17.0 comparisons. Phenotypic assays showed that most SE isolates (73%) were strong biofilm formers, while the majority of SK isolates (62%) failed to form biofilms, despite many carrying the complete curli-cell

SUBMITTER: Zhang J 

PROVIDER: S-EPMC12654831 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature