Analysis of Antimicrobial Resistance and Virulence Factors in Multidrug-Resistant <i>Streptococcus suis</i> Serotype 2 Isolates Using Whole-Genome Sequencing.

ABSTRACT: Multidrug-resistant (MDR) Streptococcus suis (S. suis) is a zoonotic pathogen capable of infecting pigs across all age groups, leading to conditions such as meningitis, arthritis, and endocarditis. In humans, infections can result in septic arthritis, meningitis, necrotizing fasciitis, and septicemia, which may be fatal. The absence of a complete genome sequence hinders comprehensive bioinformatic studies of MDR S. suis derived from pigs. In this study, we present the whole-genome sequence of MDR S. suis serotype 2 ST01 isolated from joint fluid samples obtained from pigs. Whole-genome analysis revealed that the ST01 chromosome carries 19 antibiotic resistance genes that confer resistance to major classes of antibiotic including aminoglycosides, tetracyclines, f

SUBMITTER: Zhang L 

PROVIDER: S-EPMC12654837 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature