Sex-Specific Autoimmune Comorbidity Patterns in Pemphigus Vulgaris and Bullous Pemphigoid: A Bicenter Retrospective Case-Control Study.

ABSTRACT: Background and Objectives: While pemphigus vulgaris (PV) and bullous pemphigoid (BP) have been linked to autoimmune comorbidities, the spectrum and specificity of these associations remain uncertain. We aimed to investigate the prevalence and patterns of autoimmune diseases (AIDs) in patients with PV and BP compared with age- and sex-matched controls. Materials and Methods: We conducted a bicenter, retrospective case-control study including 287 PV patients with 1148 matched controls and 284 BP patients with 1137 matched controls. Autoimmune comorbidities were identified through medical record review, and disease-specific as well as system-level associations between PV, BP, and AIDs were assessed. Results: Overall AID prevalence was lower in PV (9.4%) and BP (8.1%) than

SUBMITTER: Zorlu O 

PROVIDER: S-EPMC12654845 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature