Associations of calcium and magnesium intakes and their intake ratio with albuminuria in middle-aged and older adults.

ABSTRACT: Calcium and magnesium both work together and against each other by sharing homeostatic regulatory systems in the kidneys. Previous studies suggested that these minerals and their intake ratio were associated with chronic health conditions such as cardiovascular disease. Our objective was to investigate the association of calcium and magnesium intake and their intake ratio with albuminuria. This cross-sectional study analyzed data from a Japanese community-based cohort comprising 6,849 individuals aged ≥40 years (mean age 68.8 years, 51.3% women). Energy-adjusted dietary intake of calcium and magnesium and the calcium-to-magnesium intake ratio were derived from a validated food frequency questionnaire. The outcome was spot urinary albumin-to-creatinine ratio (ACR, mg/g). Linear and logistic

SUBMITTER: Kabasawa K 

PROVIDER: S-EPMC12654892 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature