CanRisk-GP protocol: A feasibility study of incorporating proactive multifactorial breast cancer risk assessment into general practice.

ABSTRACT:

Background

CanRisk is a risk assessment tool that implements the BOADICEA multifactorial breast cancer risk model. The BOADICEA model is recommended for use by the National Institute for Health and Care Excellence (NICE) in English, Welsh, and Northern Irish secondary/tertiary care to identify women who may be at moderate or high risk of developing breast cancer. BOADICEA combines information on cancer family history, demographic, lifestyle, hormonal risk factors and mammographic density with polygenic scores (PGS). Offering risk assessment using CanRisk in general practice has the potential to identify more women at moderate or high risk of developing breast cancer and improve their management and the appropriateness of referrals to secondary/tertiary care.

Materials and method

SUBMITTER: Stutzin Donoso F 

PROVIDER: S-EPMC12654911 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature