Multi-Response Modeling for Bio-Compound Ultrasound-Assisted Extraction (UAE) from Matico (<i>Piper aduncum</i> L.) and Chacruna (<i>Psychotria viridis</i> Ruiz & Pav.) Leaves Originating in the Peruvian Amazon.

ABSTRACT: Medicinal plants play an essential role in the food, pharmaceutical, and cosmetic industries due to their ability to prevent and treat diseases. In this study, a three-factor, three-level Box-Behnken experimental design (BBD) with response surface methodology (RSM) was used to maximize the conditions of ultrasound-assisted extraction (UAE) of bioactive compounds from matico and chacruna leaves in terms of total extraction yield (TEY), total phenolic content (TPC) and antioxidant activity (AA) using ABTS and DPPH assays. The effect of methanol concentration (X1: 25%, 50%, and 75%), time (X2: 3, 6, and 9 min), and power (X3: 90, 270, and 450 W) was evaluated as independent variables. The experimental results were fitted to second-order polynomial models, and multiple regression analysis and

SUBMITTER: Rafael-Saldana R 

PROVIDER: S-EPMC12655001 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature